Picras-3-en-21-oic acid, 15-[[(2E)-3,4-dimethyl-1-oxo-2-penten-1-yl]oxy]-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxo-, methyl ester, (11β,12α,15β)-
Bruceantin
CAS: 41451-75-6
Molecular Formula: C28H36O11
Picras-3-en-21-oic acid, 15-[[(2E)-3,4-dimethyl-1-oxo-2-penten-1-yl]oxy]-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxo-, methyl ester, (11β,12α,15β)- - Names and Identifiers
Picras-3-en-21-oic acid, 15-[[(2E)-3,4-dimethyl-1-oxo-2-penten-1-yl]oxy]-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxo-, methyl ester, (11β,12α,15β)- - Physico-chemical Properties
| Molecular Formula | C28H36O11 |
| Molar Mass | 548.58 |
| Density | 1.2262 (rough estimate) |
| Melting Point | 225-226℃ |
| Boling Point | 540.78°C (rough estimate) |
| Specific Rotation(α) | D25 -43° (c = 0.31 in pyridine) |
| Solubility | Soluble in methanol, ethanol, chloroform, ether and other organic solvents. |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 8.81±0.70(Predicted) |
| Storage Condition | -20°C Freezer |
| Refractive Index | 1.5970 (estimate) |
| MDL | MFCD00866510 |
| Physical and Chemical Properties | Crow gall pavilion is a white crystalline powder, insoluble in water, soluble in methanol, ethanol, chloroform, ether and other organic solvents. |
| Use | Crow gall pavilion is a plant of bitter wood family anti-dysentery Brucea javanica antidysenterica Mill. Brucea javanica B javacina (l.)Merr. Seeds can be used for content determination, identification, pharmacological experiments, etc. |
Picras-3-en-21-oic acid, 15-[[(2E)-3,4-dimethyl-1-oxo-2-penten-1-yl]oxy]-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxo-, methyl ester, (11β,12α,15β)- - Risk and Safety
| Toxicity | LD50 in male, female mice (mg/kg): 1.95, 2.58 i.v. (Castles) |
Picras-3-en-21-oic acid, 15-[[(2E)-3,4-dimethyl-1-oxo-2-penten-1-yl]oxy]-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxo-, methyl ester, (11β,12α,15β)- - Introduction
Open Data Unverified Data
Bioactive Bruceantin(NSC165563), which can be extracted from Brucea javanica dysentery, is inhibitory to B16 melanoma, colon cancer 38,L1210 and leukemia P388.
Category Toxic
Last Update：2024-04-09 19:43:38
Picras-3-en-21-oic acid, 15-[[(2E)-3,4-dimethyl-1-oxo-2-penten-1-yl]oxy]-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxo-, methyl ester, (11β,12α,15β)- - Reference Information
Open Data Unverified Data
| properties | crow gall pavilion is a white crystalline powder, insoluble in water, soluble in methanol, ethanol, chloroform, ether and other organic solvents. |
| apply | crow gall pavilion as anti-dysentery Brucea brucea antidysenterica Mill. Brucea brucea B javacina(L.)Merr. Seeds can be used for content determination, identification, pharmacological experiments, etc. |
| biological activity | Bruceantin(NSC165563) can be extracted from javanica javanica and has inhibitory effect on B16 melanoma, colon cancer 38,L1210 and leukemia P388. |
| category | toxic substances |
Last Update：2024-04-09 19:43:38
![Picras-3-en-21-oic acid, 15-[[(2E)-3,4-dimethyl-1-oxo-2-penten-1-yl]oxy]-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxo-, methyl ester, (11β,12α,15β)-](http://res.chembk.com/assets/images/structure/106940.png)
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Product Name: Bruceantin Visit Supplier Webpage Request for quotation
CAS: 41451-75-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 41451-75-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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